Potential therapeutic exploitation of the pulmonary polyamine uptake system.

In this brief communication, we describe the existence o f a pulmonary polyamine uptake system. We discuss the presence o f similar uptake systems in a numbcr o f other cell typcs. in particular certain tumour cells. Finally, we discuss the possible therapeutic exploitation of this pulmonary polyaminc uptake system. in particular, in relation to the design of novel anticancer agents and better radioprotective agents and finally its possible exploitation in antiprotozoal chemot herapy.